Reshaping the Lipid Landscape: Using High-Resolution lon Mobility To Untangle the Lipidome
Kim Ekroos, PhD
Lipids are fundamental for our existence; these diverse molecules regulate cell membrane dynamics, store energy and serve as precursors of bioactive metabolites. We are only scratching the surface in lipid science, and our understanding grows alongside the new analytical tools being developed. High-resolution ion mobility-mass spectrometry (HRIM-MS) offers exciting insights into structural details of lipids and the impact of altered metabolite pathways on the pathogenesis of many diseases.
In this webinar, Dr. Kim Ekroos explains how an HRIM-MS technique based on structures for lossless ion manipulation (SLIM) technology is enabling him to dissect the metabolic glycosphingolipid map in Parkinson's disease.
What can you expect to learn by watching?
- Understand the role of sphingolipids in neurodegenerative diseases
- Learn about SLIM technology and HRIM-MS
- Learn how HRIM-MS provides a level of detail within complex glycosphingolipids not possible with other methods