Hurrah for HRIM
Based on SLIM digital separation technology, high-resolution ion mobility (HRIM) enables best-in class biomolecule separation. HRIM separates and characterizes complex molecules with single-pass resolving power of >250 — providing higher resolution than current ion mobility or liquid chromatography (LC) separation techniques.
Incorporating HRIM into traditional analytical workflows:
- Increases reproducibility based on gas phase separations
- Improves confidence in separation data
- Improves baseline separation of isomeric and isobaric analytes
- Reduces dependence on separation by liquid chromatography
To combat disease, we need to look beyond genomics to the study of proteins, lipids, metabolites and other molecules that have the potential to be more indicative of disease.
In absence of high-resolution and throughput, pharmaceutical and clinical researchers struggle to identify clinically significant molecules when using existing separations technologies. These deficiencies limit the characterization of biologic therapeutics and slow biomarker discovery which are crucial to the development of more effective therapeutics and diagnostic assays.