Application Notes

Revealing Lipid Diversity & Structural Insights with High-Resolution Ion Mobility

Author(s)

Allison Reardon

Abstract

The following work showcases the high-resolution ion mobility (HRIM) MOBIE® system and highlights the capability to reveal new, previously hidden lipid features uncovering the rich diversity present in lipidomic samples.

Customer Intro

Problem

Solution

Summary

Abstract

Lipids are structurally complex and rich in isomers, making detailed analysis essential for understanding their biological roles and disease associations.
High-resolution ion mobility (HRIM) significantly outperforms conventional techniques in separating lipid isomers.
HRIM enables the discovery of previously undetectable lipid features and provides new structure-function correlations

Results